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Blottie's five remaining pups at ten weeks old and more DNA testing

19/2/2018

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The five remaining pups of Blottie's litter of ten pups now ten weeks old, had their second Distemper, Hepatitis and Parvo (DHP) vaccination along with the drops up the nose for Kennel Cough (KC) today. All went well and I took the vet visiting to do the puppy jabs, as an opportunity to get them to take blood samples from Ernest, Blottie and Bumble for DNA tests I want to get done for them using the LABOKLIN VETERINARY DIAGNOSTIC LABORATORY (UK). It's time to invest the big litter Blottie blessed me with, back in to the Poundlane spaniel project.
Ernest's 1/4 Poodle bit goes back to our Reggie who is already Progressive Retinal Atrophy (prcd-PRA) ​tested clear. His Cavalier bit, his  Dad, Toby and maternal Grandmother, Dolly are Episodic Falling + Dry Eye Curly Coat syndrome tested clear. I've sent off bloods for him to be tested with the Poodle DNA Bundle: DM exon2 + MH + NE + prcd-PRA option 1 + vWD1, although he should be clear for prcd-PRA, because his Poodle Grandfather is clear. This bundle still works out cheaper to pay for than paying for the other four genetic tests individually. I have now realized looking on their website there are two new tests I would of liked to of got done for him Progressive retinal atrophy ( rcd4-PRA) / LOPRA and Macrothrombocytopenia ( MTC-D ). I will get them done the next time I have the vet visiting us.
With Blottie and Bumble being Brittany cross Cavalier, I already know through parental genetic testing and testing them, that they are clear for  Episodic Falling + Dry Eye Curly Coat syndrome. So for their Cavalier side they are now being checked for Degenerative Myelopathy / Degenerative Radiculomyelopathy) DM (Exon 2) +  Hyperuricosuria / Urate Stones (HUU, SLC) ​+  ​MH (Malignant Hyperthermia) +  Macrothrombocytopenia ( MTC-D ) ​+ Muscular Dystrophy (MD). I could of opted to just test their Brittany Dad, Henry for  C3 Deficiency (Complement Component 3 deficiency) saving the cost of one test, but by the time I pay the vet to take blood from another dog and as you already were taking blood from the his two daughters, I decided to just get them tested for  C3 Deficiency (Complement Component 3 deficiency).
​
All three were really good to have their bloods taken. The vet was impressed with how good they were, especially as with Ernest and Bumble she had to take blood twice, as the first withdrawal was not quite enough to fill each test tube for each test. They say you need between 0.5 ml to 1 ml of whole blood for each test. Turn around for these tests are from 1 to 3 weeks. Fingers crossed. Hoping not to get a spoke in my wheel.
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    “The greatest pleasure of a dog is that you may make a fool of yourself with him, and not only will he not scold you,but he will make a fool of himself, too.” 
    ― Samuel Butler
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    Me (Jane) with Puddin' and Teagol, waiting patiently to flush a patch of kale, December 2019

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    Hello, I am Jane!
    You might of guessed, I love dogs. My family and me are situated in the North Devon countryside, England, United Kingdom. Our home is occupied by my husband, David, our children, pack of dogs and me.
    On this page you can find out what we are up to.
    ​Watch our litters growing day by day.
    Also regular updates on how our pups are getting on in their new homes.
    If you want to know more about what we are doing, you can ring me (Jane) on 01769 560969 for a friendly chat. 

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